Amos A M, McRoberts J W
Department of Surgery, University of Kentucky, Chandler Medical Center, Lexington 40536-0084, USA.
Urology. 1998 Aug;52(2):331-5. doi: 10.1016/s0090-4295(98)00192-7.
A norepinephrine producing right adrenal pheochromocytoma was associated with bilateral adrenal hyperplasia and clinically and biochemically evident Cushing's syndrome. Ectopic adrenocorticotropin production was suspected, but the six criteria for proof of ectopic adrenocorticotropin production could not be demonstrated. The diagnosis of Cushing's syndrome from ectopic hormone production by a pheochromocytoma requires a high index of suspicion and extensive biochemical and radiographic testing to confirm Cushing's syndrome, identify the cause of Cushing's syndrome, and localize the pheochromocytoma.
一例分泌去甲肾上腺素的右肾上腺嗜铬细胞瘤合并双侧肾上腺增生，且有临床及生化证据支持的库欣综合征。怀疑有异位促肾上腺皮质激素分泌，但未能证实异位促肾上腺皮质激素分泌的六项标准。嗜铬细胞瘤异位激素分泌导致库欣综合征的诊断需要高度怀疑，并进行广泛的生化和影像学检查，以确诊库欣综合征、确定其病因并定位嗜铬细胞瘤。
