Kimmig J M, Heinkel K, Ensslin H
Z Gastroenterol. 1976 Sep;14(5):531-5.
Studies of motility of the stomach in 10 test-persons resulted in a significant reduction of motility after a 2-day period of perorally intake of Lyspafen. The active motoric substance is diffenoxin-hydrochloride. An addition of 0,025 mg Atropin sulfate could increase the effect. The effect is independent of the clinical diagnose. A "runaway" could be explained by an intolerance against lactose. The waves of type I are less influenced, such as the frequency of the waves of contraction.
对10名受试人员的胃动力研究结果显示，在经口摄入利司哌芬2天后，胃动力显著降低。活性运动物质为盐酸地芬诺辛。添加0.025毫克硫酸阿托品可增强效果。该效果与临床诊断无关。“失控”现象可归因于对乳糖不耐受。I型波受影响较小，比如收缩波的频率。
