Tozzi-Ciancarelli M G, Di Massimo C, Ascani G, Corbacelli A
Department of STB, School of Medicine, University of L'Aquila, Italy.
Clin Hemorheol Microcirc. 1998 Jul;18(2-3):151-6.
A short-term in vitro experimental study was performed to analyze the effects of metallic miniplates used in maxillo-facial rigid internal fixation on some functional features of human erythrocytes that represent a pivotal rheological component for correct blood flow in the tissular area surrounding metallic implants. In our working conditions, no interference on osmotic fragility, intracellular ATP content and spontaneous hemolysis was observed. Conversely, a statistically significant increase of rigidity in the deeper lipid region of erythrocyte membrane was verified. On the basis of our results, the in vitro erythrocyte modifications after 18 h of whole blood/metallic device contact are relatively small and negligible.
进行了一项短期体外实验研究，以分析用于颌面坚固内固定的金属微型钢板对人红细胞某些功能特性的影响，这些特性是金属植入物周围组织区域正确血流的关键流变学组成部分。在我们的工作条件下，未观察到对渗透脆性、细胞内ATP含量和自发溶血的干扰。相反，证实红细胞膜较深脂质区域的刚性有统计学意义的增加。根据我们的结果，全血/金属装置接触18小时后体外红细胞的变化相对较小且可忽略不计。
