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经皮腔内血管成形术治疗肾血管性高血压:序贯前瞻性研究

Percutaneous transluminal angioplasty in the treatment of renovascular hypertension: sequential prospective study.

作者信息

Miranda Júnior F, Perez M del C, Plavnik F, Francisco Júnior J, Burihan E

机构信息

Department of Surgery and Nephrology, Universidade Federal de São Paulo, Escola Paulista de Medicina, Brazil.

出版信息

Sao Paulo Med J. 1998 Jan-Feb;116(1):1613-7. doi: 10.1590/s1516-31801998000100004.

DOI:10.1590/s1516-31801998000100004
PMID:9699383
Abstract

OBJECTIVE

To evaluate the use of percutaneous transluminal renal angioplasty (PTRA) in the treatment of renal vascular hypertension.

DESIGN

Sequential prospective PTRA treatment of severe arterial hypertension, screening by the captopril test, confirmed by renal arteriography, and the result evaluated by post-PTRA arteriography, blood pressure measurement and renal function. SITE: Vascular Surgery, angioradiology sector, and Nephrology outpatients department of the Federal University of São Paulo-Paulista School of Medicine, São Paulo, Brazil, a tertiary health-care institution.

PARTICIPANTS

PTRA was employed on 32 patients screened by clinical examination, captopril test and renal arteriography.

EVALUATION

PTRA results were evaluated by the criteria of the Cooperative Study of Renovascular Hypertension.

RESULTS

After PTRA the completion arteriography showed no renal stenosis in 24 patients (75%), residual stenosis (20-50%) in 3 (9.4%) and no change in 5 (15.6%). The blood pressure results were: 3 patients (9.4%) were cured, 24 (75%) improved and 5 (15.6%) were unchanged. We observed normal renal function before and after PTRA in 25 patients (78%); altered pre- and improved post-PTRA in 2 (6.3%); post-PTRA remained unaltered in 2 (6.3%); and altered pre- and worsened post-PTRA in 3 (9.4%). Recurrence of stenosis occurred in one patient after 8 months.

CONCLUSIONS

PTRA is a convenient procedure, relatively safe and an effective complementary method of medical therapy for controlling renovascular hypertension.

摘要

目的

评估经皮腔内肾血管成形术(PTRA)治疗肾血管性高血压的效果。

设计

对严重动脉高血压患者进行序贯前瞻性PTRA治疗,通过卡托普利试验进行筛查,肾动脉造影确诊,并通过PTRA术后动脉造影、血压测量和肾功能评估结果。地点:巴西圣保罗联邦大学保罗医科大学的血管外科、血管放射科和肾病门诊,这是一家三级医疗机构。

参与者

对32例经临床检查、卡托普利试验和肾动脉造影筛查的患者进行了PTRA治疗。

评估

根据肾血管性高血压合作研究的标准评估PTRA结果。

结果

PTRA术后,24例患者(75%)完成动脉造影显示无肾狭窄,3例(9.4%)有残余狭窄(20%-50%),5例(15.6%)无变化。血压结果为:3例患者(9.4%)治愈,24例(75%)改善,5例(15.6%)无变化。我们观察到25例患者(78%)PTRA前后肾功能正常;2例(6.3%)术前异常但PTRA术后改善;2例(6.3%)PTRA术后仍无变化;3例(9.4%)术前异常且PTRA术后恶化。1例患者在8个月后出现狭窄复发。

结论

PTRA是一种简便、相对安全且有效的控制肾血管性高血压的辅助治疗方法。

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Percutaneous transluminal angioplasty in the treatment of renovascular hypertension: sequential prospective study.经皮腔内血管成形术治疗肾血管性高血压:序贯前瞻性研究
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