Greene J H, Klinger J R
Division of Pulmonary, Sleep, and Critical Care Medicine, Rhode Island Hospital, Providence, USA.
Crit Care Clin. 1998 Jul;14(3):387-409. doi: 10.1016/s0749-0704(05)70007-5.
Nitric oxide is an endothelial relaxing factor. When given as an inhalational agent in the acute respiratory distress syndrome (ARDS), it vasodilates well ventilated areas of lung and improves oxygenation. Nitric oxide is a highly reactive molecule with myriad biologic effects, both potentially beneficial and toxic; its use as an inhalational agent in ARDS is experimental. This article reviews the available studies of inhaled nitric oxide.
一氧化氮是一种内皮舒张因子。在急性呼吸窘迫综合征（ARDS）中作为吸入剂使用时，它可使肺的通气良好区域血管扩张并改善氧合。一氧化氮是一种具有多种生物学效应的高反应性分子，这些效应既有潜在益处也有毒性；其在ARDS中作为吸入剂的应用尚处于实验阶段。本文综述了关于吸入一氧化氮的现有研究。
