Hansmann H J, Wunsch C, Darge K, Schneider B, Hess T, Grüber-Hoffmann B, Richter G M, Kauffmann G W
Abteilung Radiodiagnostik, Radiologische Universitätsklinik Heidelberg.
Radiologe. 1998 Jun;38(6):523-9. doi: 10.1007/s001170050387.
Adjuvant chemotherapy has significantly improved the prognosis of patients with bone sarcomas. Preoperative diagnostic imaging of tumor response to such therapy has become a mainstay for the assessment of prognosis, planning of surgery and further treatment. During therapy, responding tumors show characteristic changes on conventional radiography, angiography, sonography, radionuclide studies, CT and MR. The usefulness and the limitations of each imaging modality in assessing response to therapy are reviewed. The diagnostic importance of specific changes such as tumor volume reduction, calcification and tumor vascularization is discussed.
辅助化疗显著改善了骨肉瘤患者的预后。术前对肿瘤对该治疗反应的诊断性影像学检查已成为评估预后、规划手术和进一步治疗的主要手段。在治疗过程中，有反应的肿瘤在传统X线摄影、血管造影、超声、放射性核素研究、CT和MR上显示出特征性变化。本文综述了每种影像学检查方法在评估治疗反应中的作用及局限性。讨论了肿瘤体积缩小、钙化和肿瘤血管形成等特定变化的诊断意义。
