Arzumanian V G, Mokronosova M A, Samuilova T L, Gervazieva V B
Institute of Microbiology, Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 1998 May-Jun(3):10-3.
Colonization by yeast-like flora and its composition on the skin of patients with atopic dermatitis (AD) in comparison with those on the skin of patients with skin diseases of nonatopic etiology and healthy subjects were studied. Inoculations from affected and unaffected sites of the skin were made by the contact method with the use of bacteriological plates with antibiotic-containing solid agar medium. The study revealed that 39% of AD patients, 45% of patients with other skin diseases and 3% of healthy subjects had yeast-like fungi of their skin, Candida spp. (53%) and Rhodotorula spp. (21%) occurring most frequently. In patients with a severe course of AD the tendency towards the preferable colonization of affected sites of the skin was observed: in these cases yeasts occurred 2.5-5 times more frequently than in patients with the mild and moderate course of AD.
研究了特应性皮炎（AD）患者皮肤与非特应性病因皮肤病患者及健康受试者皮肤的酵母样菌群定植情况及其组成。采用含抗生素固体琼脂培养基的细菌学平板，通过接触法从皮肤的受累和未受累部位进行接种。研究发现，39%的AD患者、45%的其他皮肤病患者和3%的健康受试者皮肤存在酵母样真菌，其中念珠菌属（53%）和红酵母属（21%）最为常见。在AD病情严重的患者中，观察到皮肤受累部位有更易定植的倾向：在这些病例中，酵母出现的频率比AD病情轻度和中度的患者高2.5至5倍。
