Fariña M C, Tarín N, Grilli R, Soriano M L, Sarasa J L, Martín L, Requena L
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
J Surg Oncol. 1998 Jul;68(3):199-203. doi: 10.1002/(sici)1096-9098(199807)68:3<199::aid-jso13>3.0.co;2-x.
Acquired hypertrichosis lanuginosa is a rare cutaneous disorder usually associated with internal malignancy that consists of the development of abnormal hair growth of the lanugo type, often confined to the skin of the face and neck, although other areas also may be involved. We report on a 66-year-old woman with a metastatic ductal infiltrating carcinoma of the breast who developed growth of fine lanugo type hair on her face and progressive growth of the hair of eyebrows and eyelashes. We review the literature on this uncommon paraneoplastic cutaneous disorder emphasizing the pathogenic mechanisms that have been proposed to explain the striking overgrowth of lanugo type hair.
获得性胎毛增多症是一种罕见的皮肤疾病，通常与内部恶性肿瘤相关，其特征是出现胎毛型异常毛发增多，常局限于面部和颈部皮肤，不过其他部位也可能受累。我们报告了一名66岁患有乳腺转移性导管浸润癌的女性，她面部出现了纤细的胎毛型毛发增长，眉毛和睫毛也逐渐变长。我们回顾了关于这种罕见的副肿瘤性皮肤疾病的文献，重点阐述了为解释胎毛型毛发显著过度生长而提出的致病机制。
