两名因苯海拉明中毒的兄弟姐妹：代理型做作性障碍病例

Two siblings poisoned with diphenhydramine: a case of factitious disorder by proxy.

作者信息

Arnold S M, Arnholz D, Garyfallou G T, Heard K

机构信息

Colorado Permanente Medical Group, University of Colorado School of Medicine, The Children's Hospital, Denver, USA.

出版信息

Ann Emerg Med. 1998 Aug;32(2):256-9. doi: 10.1016/s0196-0644(98)70146-5.

DOI:10.1016/s0196-0644(98)70146-5

PMID:9701313

Abstract

We report a case of factitious disorder by proxy (FDBP), formerly known as Munchausen syndrome by proxy, in which 2 siblings were poisoned with diphenhydramine. Although diphenhydramine is a readily available medication, no report of its use as the sole agent in an FDBP case was found in a literature search. Although sibling involvement in FDBP is well documented, this is the first case report of 2 siblings hospitalized simultaneously because of intentional poisoning with the same substance. Finally, the use of physostigmine to definitively diagnose anticholinergic poisoning in a case of FDBP has not previously been described.

摘要

我们报告了一例代理型做作性障碍（FDBP，以前称为代理型孟乔森综合征），其中两名兄弟姐妹被苯海拉明下毒。尽管苯海拉明是一种容易获得的药物，但在文献检索中未发现其作为FDBP病例中唯一中毒药物的报告。虽然兄弟姐妹参与FDBP已有充分记录，但这是首例关于两名兄弟姐妹因同一物质故意中毒而同时住院的病例报告。最后，使用毒扁豆碱来明确诊断FDBP病例中的抗胆碱能中毒，此前尚无相关描述。