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[小肠恶性肿瘤。附7例报告。临床讨论及文献复习]

[Malignant neoplasia of the small intestine. Apropos of 7 cases. Clinical discussion and review of the literature].

作者信息

Bianchi E, De Monti M, Miani S, Stringhi E, Scorza R

机构信息

Cattedra di Chirurgia Generale, Ospedale di Treviglio (Bergamo), Università degli Studi, Milano.

出版信息

Minerva Chir. 1998 Apr;53(4):289-98.

PMID:9701984
Abstract

The authors report seven cases of primary malignancies of the small intestine observed and treated between 1989 and 1995 at the First Surgical Division of Treviglio Hospital. Three patients were affected by adenocarcinomas (two involving the duodenum and one the jejunum), two patients had non-endocrine carcinoid tumors of the ileum, one presented a jejunal liposarcoma and one a lymphoma of the ileum. Four patients died (respectively at three months, 15 months, 18 months and five years after surgical intervention). Three patients are still alive. The early clinical features of these malignancies are typically vague and non specific and for this reason the disease is often diagnosed at an advanced stage. The prognosis of these lesions is generally poor owing to the diffusion of the disease at the time of diagnosis. In fact these neoplasms are preoperatively identified only in 27-72%. The percentage of surgical removal ranges between 65 and 80% according to the recent literature. This study is aimed at analysing the clinical and pathologic characteristics of the observed cases and the difficulties of the diagnostic procedure. The adopted surgical techniques and the outcome of the operative treatment are also examined.

摘要

作者报告了1989年至1995年期间在特雷维廖医院第一外科观察和治疗的7例小肠原发性恶性肿瘤病例。3例患者患有腺癌(2例累及十二指肠,1例累及空肠),2例患者患有回肠非内分泌类癌肿瘤,1例为空肠脂肪肉瘤,1例为回肠淋巴瘤。4例患者死亡(分别在手术干预后3个月、15个月、18个月和5年)。3例患者仍然存活。这些恶性肿瘤的早期临床特征通常模糊且不具特异性,因此该病常被诊断为晚期。由于疾病在诊断时已扩散,这些病变的预后通常较差。事实上,这些肿瘤术前仅在27%至72%的病例中被识别。根据最近的文献,手术切除率在65%至80%之间。本研究旨在分析观察病例的临床和病理特征以及诊断过程中的困难。同时还检查了所采用的手术技术和手术治疗的结果。

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