心律失常与猝死的分子遗传学
The molecular genetics of arrhythmias and sudden death.
作者信息
Brugada R, Roberts R
机构信息
Department of Medicine/Cardiology, Baylor College of Medicine, Houston, TX 77030, USA.
出版信息
Clin Cardiol. 1998 Aug;21(8):553-60. doi: 10.1002/clc.4960210805.
Abstract
The current status of the research in genetics of cardiac diseases causing sudden death is reviewed. Few techniques will impact medicine as will those of molecular biology. The identification of the gene-causing diseases will allow the use of better preventive, diagnostic, and therapeutic options. From genetic counseling at present to gene therapy in the future, the new challenge for the clinician will be to acquire the new information provided by molecular biology and apply it at the bedside to improve the quality of life for the patient.
摘要
本文综述了导致猝死的心脏病遗传学研究现状。很少有技术能像分子生物学技术那样对医学产生重大影响。致病基因的鉴定将使人们能够采用更好的预防、诊断和治疗方法。从目前的遗传咨询到未来的基因治疗，临床医生面临的新挑战将是获取分子生物学提供的新信息，并将其应用于临床，以提高患者的生活质量。
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