Kronz J D, Nicol T L, Rosenthal D L, Ali S Z
Johns K. Frost Cytopathology Laboratory, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland 21287-6940, USA.
Diagn Cytopathol. 1998 Aug;19(2):127-30. doi: 10.1002/(sici)1097-0339(199808)19:2<127::aid-dc13>3.0.co;2-h.
Malignant Sertoli-cell tumors of the testis are exceedingly rare. We present cytopathologic findings in pelvic metastasis of such a tumor in a 45-year-old man, diagnosed on fine-needle aspiration, 2 months after radical orchiectomy. Ultrasound-guided aspirate showed tissue fragments and isolated discohesive tumor cells with characteristics of testicular Sertoli cells. Immunoperoxidase (IPOX) studies and histopathologic correlation with the primary testicular tumor are also presented. Cytopathologic features complimented by IPOX studies should allow an accurate diagnosis of this rare entity, when seen at metastatic sites.
睾丸恶性支持细胞瘤极为罕见。我们报告了一名45岁男性此类肿瘤盆腔转移的细胞病理学发现，该病例在根治性睾丸切除术后2个月通过细针穿刺确诊。超声引导下穿刺显示组织碎片和孤立的、无黏附性的肿瘤细胞，具有睾丸支持细胞的特征。还介绍了免疫过氧化物酶（IPOX）研究以及与原发性睾丸肿瘤的组织病理学相关性。当在转移部位发现时，结合IPOX研究的细胞病理学特征应能准确诊断这种罕见疾病。
