• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Effect of nonsteroidal anti-inflammatory drugs on lipid peroxidation by hydroxyl radical.

作者信息

Tsujimoto Y, Saitoh K, Kashima M, Shiozawa A, Kozuka M, Hashizume H, Kimura K, Yamazaki M, Fujii A

机构信息

Department of Endodontics, Nihon University School of Dentistry at Matsudo, Chiba, Japan.

出版信息

Gen Pharmacol. 1998 Sep;31(3):405-8. doi: 10.1016/s0306-3623(98)00044-5.

DOI:10.1016/s0306-3623(98)00044-5
PMID:9703209
Abstract
  1. Effects of acetaminophen and sodium salicylate on hydoxyl radical elimination were studied using an electron-spin-resonance spin-trapping method. The effects of these agents on lipid peroxidation of the human erythrocyte membrane were also investigated by the thiobarbituric acid method. 2. Acetaminophen and sodium salicylate depressed hydroxyl radical generated by Cu2+/H2O2. 3. Acetaminophen inhibited Cu2+/H2O2-dependent lipid peroxidation; however, sodium salicylate enhanced Cu2+/H2O2-dependent lipid peroxidation.
摘要

相似文献

1
Effect of nonsteroidal anti-inflammatory drugs on lipid peroxidation by hydroxyl radical.
Gen Pharmacol. 1998 Sep;31(3):405-8. doi: 10.1016/s0306-3623(98)00044-5.
2
Effects of catechins on superoxide and hydroxyl radical.儿茶素对超氧阴离子自由基和羟基自由基的影响。
Chem Pharm Bull (Tokyo). 1999 Feb;47(2):279-83. doi: 10.1248/cpb.47.279.
3
Inhibitory effect of eugenol on Cu2+-catalyzed lipid peroxidation in human erythrocyte membranes.丁香酚对人红细胞膜中铜离子催化的脂质过氧化的抑制作用。
Int J Biochem. 1989;21(7):745-9. doi: 10.1016/0020-711x(89)90205-x.
4
Ferric(III) ions inhibits copper(II)/hydrogen peroxide-catalyzing lipid peroxidation in human erythrocyte membranes.
Int J Biochem. 1992 May;24(5):795-8. doi: 10.1016/0020-711x(92)90014-r.
5
Mechanisms of active oxygen species reduction by non-steroidal anti-inflammatory drugs.
Int J Biochem Cell Biol. 1997 Mar;29(3):437-46. doi: 10.1016/s1357-2725(96)00144-6.
6
In vitro effects of NSAIDS and paracetamol on oxidative stress-related parameters of human erythrocytes.非甾体抗炎药和对乙酰氨基酚对人红细胞氧化应激相关参数的体外作用。
Exp Toxicol Pathol. 2001 Jun;53(2-3):133-40. doi: 10.1078/0940-2993-00179.
7
Lipid peroxidation induced by phenylbutazone radicals.
Life Sci. 2002 Apr 19;70(22):2611-21. doi: 10.1016/s0024-3205(02)01554-0.
8
Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers.酚类衍生物（对乙酰氨基酚、水杨酸盐和5-氨基水杨酸盐）作为膜脂质过氧化抑制剂和过氧自由基清除剂的作用。
Arch Biochem Biophys. 1994 Nov 15;315(1):161-9. doi: 10.1006/abbi.1994.1485.
9
Hydroxyl radical formation and lipid peroxidation enhancement by chromium. In vitro study.铬诱导的羟基自由基形成及脂质过氧化增强。体外研究。
Biol Trace Elem Res. 1992 Jan-Mar;32:161-70. doi: 10.1007/BF02784601.
10
Protective effect of erythropoietin on the oxidative damage of erythrocyte membrane by hydroxyl radical.促红细胞生成素对羟自由基所致红细胞膜氧化损伤的保护作用。
Biochem Pharmacol. 2000 Feb 15;59(4):419-25. doi: 10.1016/s0006-2952(99)00277-4.

引用本文的文献

1
Effects of dipyrone on inflammatory infiltration and oxidative metabolism in gastric mucosa: comparison with acetaminophen and diclofenac.安乃近对胃黏膜炎症浸润和氧化代谢的影响：与对乙酰氨基酚和双氯芬酸的比较。
Dig Dis Sci. 2002 Jun;47(6):1389-98. doi: 10.1023/a:1015395103160.
2
Gastric toxicity of racemic ketoprofen and its enantiomers in rat: oxygen radical generation and COX-expression.消旋酮洛芬及其对映体在大鼠体内的胃毒性：氧自由基生成与环氧化酶表达
Inflamm Res. 2002 Feb;51(2):51-7. doi: 10.1007/BF02683999.