伴有克隆性染色体改变的骨样骨瘤和成骨细胞瘤。

Dal Cin P, Sciot R, Samson I, De Wever I, Van den Berghe H

Centre for Human Genetics, Leuven, Belgium.

Br J Cancer. 1998 Aug;78(3):344-8. doi: 10.1038/bjc.1998.496.

We cytogenetically investigated six osteoid osteomas, one osteoblastoma and one aggressive osteoblastoma, and observed clonal structural changes in one osteoid osteoma and in the aggressive osteoblastoma. Clonal chromosome changes had not been reported previously in osteoid osteoma, whereas the only reported chromosome change in osteoblastoma was different from the one presented here.

我们对6例骨样骨瘤、1例骨母细胞瘤和1例侵袭性骨母细胞瘤进行了细胞遗传学研究，在1例骨样骨瘤和1例侵袭性骨母细胞瘤中观察到克隆性结构改变。此前尚未有骨样骨瘤出现克隆性染色体改变的报道，而骨母细胞瘤中唯一报道过的染色体改变与本文所呈现的不同。