• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.

作者信息

Nargund R P, Patchett A A, Bach M A, Murphy M G, Smith R G

机构信息

Departments of Medicinal Chemistry, Clinical Pharmacology, Clinical Sciences, and Biochemistry and Physiology, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.

出版信息

J Med Chem. 1998 Aug 13;41(17):3103-27. doi: 10.1021/jm970342o.

DOI:10.1021/jm970342o
PMID:9703459
Abstract
摘要

相似文献

1
Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.
J Med Chem. 1998 Aug 13;41(17):3103-27. doi: 10.1021/jm970342o.
2
Melanin-concentrating hormone stimulates human growth hormone secretion: a novel effect of MCH on the hypothalamic-pituitary axis.促黑素细胞激素刺激人类生长激素分泌:促黑素细胞激素对下丘脑 - 垂体轴的一种新作用。
Am J Physiol Endocrinol Metab. 2006 May;290(5):E982-8. doi: 10.1152/ajpendo.00138.2005.
3
Structure and regulation of the growth hormone secretagogue receptor.生长激素促分泌素受体的结构与调控
Minerva Endocrinol. 2002 Dec;27(4):243-56.
4
Age-related variations of the GH response to GH secretagogues in humans.人类生长激素(GH)对生长激素促分泌素反应的年龄相关变化。
J Endocrinol Invest. 2002;25(10 Suppl):42-3.
5
Growth hormone secretagogues: discovery of small orally active molecules by peptidomimetic strategies.生长激素促分泌素:通过拟肽策略发现口服活性小分子
Prog Med Chem. 2002;39:173-214. doi: 10.1016/s0079-6468(08)70071-7.
6
Growth hormone-releasing hormone and pituitary somatotrope proliferation.生长激素释放激素与垂体生长激素细胞增殖
Minerva Endocrinol. 2002 Dec;27(4):277-85.
7
Rational design, synthesis, and biological evaluation of novel growth hormone releasing factor analogues.
Biopolymers. 1995;37(2):67-88. doi: 10.1002/bip.360370204.
8
Clinical pharmacology of human growth hormone and its secretagogues.人生长激素及其促分泌素的临床药理学
Curr Drug Targets Immune Endocr Metabol Disord. 2002 Apr;2(1):27-52.
9
[Modern views on the activities of growth hormone].[关于生长激素活性的现代观点]
Pol Tyg Lek. 1976 Oct 4;31(40):1737-9.
10
Novel orally active growth hormone secretagogues.新型口服活性生长激素促分泌素
J Med Chem. 1998 Sep 10;41(19):3705-14. doi: 10.1021/jm980197u.

引用本文的文献

1
Insights on discovery, efficacy, safety and clinical applications of ghrelin receptor agonist capromorelin in veterinary medicine.在兽医学中发现、功效、安全性和临床应用方面的见解——ghrelin 受体激动剂卡泊瑞林。
Vet Res Commun. 2024 Feb;48(1):1-10. doi: 10.1007/s11259-023-10184-0. Epub 2023 Jul 26.
2
Pathophysiogenesis of mesial temporal lobe epilepsy: is prevention of damage antiepileptogenic?内侧颞叶癫痫的病理生理发生机制:预防损伤是否具有抗癫痫发生作用?
Curr Med Chem. 2014;21(6):663-88. doi: 10.2174/0929867320666131119152201.
3
Regulation and clinical assessment of growth hormone secretion.
生长激素分泌的调节与临床评估
Endocrine. 2000 Apr;12(2):137-45. doi: 10.1385/ENDO:12:2:137.
4
Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2.对生长抑素受体亚型2具有选择性的强效拟肽的合成及生物活性
Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10836-41. doi: 10.1073/pnas.95.18.10836.