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[蛋白水解物质莫里司酶对体外条件下瘢痕组织状态的影响]

[Effect of the proteolytic substance morikrase on the status of scar tissue under in vitro conditions].

作者信息

Liutova L V, Karabasova M A, Andreenko G V, Rudenskaia G N, Isaev V A, Brusov A B

机构信息

School of Biology, M.V. Lomonosov Moscow State University.

出版信息

Vopr Med Khim. 1998 May-Jun;44(3):292-5.

PMID:9703631
Abstract

Proteolytical preparation moricrasa was isolated from hepatopancreas of Paralithodes camtshatic. Moricrasa and its fractions were used for lysis of cicatricial tissue under in vitro conditions. It was found that moricrasa in concentrations 0.5 mg/ml and 2 mg/ml lysed the cicatrix during 72 and 14-16 hours, respectively. The fraction consisted of collagenolytic proteinase PC and trypsin revealed maximal activity of fraction of moricrasa was absent.

摘要

从堪察加拟石蟹的肝胰腺中分离出蛋白水解制剂moricrasa。在体外条件下,moricrasa及其组分用于溶解瘢痕组织。发现浓度为0.5mg/ml和2mg/ml的moricrasa分别在72小时和14 - 16小时内溶解瘢痕。由胶原水解蛋白酶PC和胰蛋白酶组成的组分显示出moricrasa组分的最大活性不存在。

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