Koyama N, Nishikawa Y, Yokota T
Department of Physiology, Shiga University of Medical Science, Seta, Otsu, Japan.
Neurosci Res. 1998 May;31(1):39-51. doi: 10.1016/s0168-0102(98)00021-2.
In urethane-chloralose anesthetized Japanese macaques, the distribution of nociceptive neurons within the thalamic ventrobasal (VB) complex was studied. Nociceptive specific (NS) and wide dynamic range (WDR) neurons were found in the periphery of the contralateral integument compartment of the VB complex. Thus, they formed a shell at the perimeter of this compartment with a somatotopic organization. The compartment consisted of large parts of nucleus ventralis posteromedialis (VPM) and nucleus ventralis posterolateralis, pars caudalis (VPLc). NS neurons were located more caudally than WDR neurons. In the NS zone of VPM, the forehead was represented caudally, and oral structures rostrally. In the ventral NS zone of VPM, there was a sequential representation of the tongue, gum and mandibular skin from the medial to the lateral edge. The hand was represented medially in the NS zone of VPLc, and its representation dominated in the rostral NS zone. There was a sequential representation of the cervical, thoracic, lumbar, sacral and caudal segments mediolaterally along the dorsal VPLc. In the medial half of ventral NS zone of VPLc, the upper body half was represented, and in the lateral half, the lower body half. The foot was represented at or near the medial edge of lateral half. In the rostral WDR zone, the trunk and peripheral face were represented.
在氨基甲酸乙酯-水合氯醛麻醉的日本猕猴中，研究了丘脑腹侧基底（VB）复合体中伤害性神经元的分布。在VB复合体对侧体表区的外周发现了伤害性特异性（NS）神经元和广动力范围（WDR）神经元。因此，它们在该区域的周边形成了一个具有躯体定位组织的壳。该区域由腹后内侧核（VPM）和腹后外侧核尾部（VPLc）的大部分组成。NS神经元比WDR神经元更靠尾侧。在VPM的NS区，前额在尾侧代表，口腔结构在头侧代表。在VPM的腹侧NS区，从内侧边缘到外侧边缘依次代表舌、牙龈和下颌皮肤。手在内侧被VPLc的NS区代表，并且其代表在头侧NS区占主导。沿着背侧VPLc，颈、胸、腰、骶和尾段从中线向外侧依次代表。在VPLc腹侧NS区的内侧半部分，代表上半身，在外侧半部分，代表下半身。脚在外侧半部分的内侧边缘或其附近代表。在头侧WDR区，代表躯干和外周面部。
