Whyman M R, Ruckley C V
Cheltenham General Hospital, UK.
Cardiovasc Surg. 1998 Jun;6(3):226-31. doi: 10.1016/s0967-2109(97)00142-7.
Robust clinical and scientific data to support the use of angioplasty or exercise for intermittent claudication are scanty. The purpose of this article is to explore the evidence for each of these treatments. A computer search of relevant published material. Very few randomised controlled trials are available on which to base a sound treatment policy. Currently, the evidence in favour of exercise therapy for short term improvement in symptoms is more compelling than that for angioplasty. The mechanisms of action, the magnitude of effects on walking, the relative efficacy and the hazards of the treatments are discussed. The only way to seriously address the question of which treatment is best for claudicants is by means of the randomised trial and until this has been done angioplasty will remain an expensive treatment of unproven benefit for claudication.
支持使用血管成形术或运动疗法治疗间歇性跛行的可靠临床和科学数据很少。本文旨在探讨这些治疗方法各自的证据。通过计算机检索相关已发表材料。几乎没有可作为合理治疗策略依据的随机对照试验。目前,支持运动疗法在短期内改善症状的证据比血管成形术更有说服力。文中讨论了两种治疗方法的作用机制、对行走能力影响的程度、相对疗效及风险。要认真解决哪种治疗方法对间歇性跛行患者最有效的问题,唯一途径是进行随机试验,在此之前,血管成形术对间歇性跛行而言仍将是一种益处未经证实的昂贵治疗方法。