Ceranic B J, Prasher D K, Luxon L M
Institute of Laryngology and Otology, University College, London, UK.
Audiol Neurootol. 1998 Sep-Oct;3(5):332-44. doi: 10.1159/000013803.
Spontaneous otoacoustic emissions (SOAE) have been widely studied in normal subjects, and there is evidence of their high frequency stability in repeated recordings. A study to determine the frequency stability of SOAE in 53 of 100 consecutive patients, who presented with tinnitus and in whom SOAE were recordable, was undertaken. Patients were divided into five aetiologically homogeneous subgroups: (i) those with normal hearing and no identified pathology, (ii) those with sensorineural hearing loss of unknown origin, (iii) those with normal hearing, but complaining of tinnitus related to head injury, (iv) those with endolymphatic hydrops, and (v) those with noise exposure. The control group consisted of 20 subjects, selected on the basis of recordable SOAE from 38 volunteers with normal hearing and no tinnitus. The prevalence of SOAE and their inter-session frequency stability (reproducibility and relative frequency shift) were analysed. In contrast to the controls, the tinnitus group had significantly increased frequency variability of SOAE (lower reproducibility and increased relative frequency shift). The prevalence of subjects with SOAE was not notably different between the controls and subjects with tinnitus, if the tinnitus group was considered in toto, but a striking 100% prevalence of bilaterally present SOAE was observed in the tinnitus subgroup with head injury.
自发性耳声发射（SOAE）已在正常受试者中得到广泛研究，并且有证据表明其在重复记录中具有高频稳定性。对100例连续就诊的耳鸣患者中的53例进行了一项研究，这些患者可记录到SOAE，目的是确定SOAE的频率稳定性。患者被分为五个病因学上同质的亚组：（i）听力正常且未发现病变的患者；（ii）病因不明的感音神经性听力损失患者；（iii）听力正常但抱怨与头部受伤相关耳鸣的患者；（iv）内淋巴积水患者；（v）有噪声暴露史的患者。对照组由20名受试者组成，这些受试者是从38名听力正常且无耳鸣的志愿者中根据可记录到的SOAE挑选出来的。分析了SOAE的患病率及其不同检查间的频率稳定性（再现性和相对频率偏移）。与对照组相比，耳鸣组的SOAE频率变异性显著增加（再现性降低且相对频率偏移增加）。如果将耳鸣组作为一个整体考虑，对照组和耳鸣组受试者中SOAE的患病率没有显著差异，但在头部受伤的耳鸣亚组中观察到双侧SOAE的患病率惊人地达到了100%。
