Arrizabalaga J, Casas A, Camino X, Iribarren J A, Rodríguez Arrondo F, Von Wichmann M A
Unidad de Enfermedades Infecciosas, Hospital Nuestra Señora de Aránzazu, San Sebastián.
Med Clin (Barc). 1998 Jun 27;111(3):103-4.
Hypersensitivity reactions to rifampin are relatively uncommon, but they may result in cessation of therapeutic medications.
We report our experience with oral desensitization protocol to rifampin in a group of 35 HIV-positive patients with mycobacterial disease who had some hypersensitivity reaction to this drug.
Adverse reactions with this protocol were few and easily treated.
Oral desensitization to rifampin is safe and effective, allowing some of these patients (60%) to reintroduce the drug and to reduce the time of treatment.
