米诺环素诱导的具有自身免疫特征和中性粒细胞减少症的肝炎。
Minocycline-induced hepatitis with autoimmune features and neutropenia.
作者信息
Bhat G, Jordan J, Sokalski S, Bajaj V, Marshall R, Berkelhammer C
机构信息
Department of Medicine, Christ Hospital and Medical Center, Oak Lawn, IL 60453, USA.
出版信息
J Clin Gastroenterol. 1998 Jul;27(1):74-5. doi: 10.1097/00004836-199807000-00016.
Abstract
Minocycline can cause various types of hepatotoxicity. We report an 18-year-old male who developed a delayed onset of minocycline-induced cholestatic hepatitis with autoimmune features and neutropenia. He responded to withdrawal of the drug and a short course of corticosteroids. If minocycline is to be administered, then periodic monitoring for hepatoxicity is recommended.
摘要
米诺环素可引起多种类型的肝毒性。我们报告一名18岁男性，他出现了迟发性米诺环素诱导的胆汁淤积性肝炎，伴有自身免疫特征和中性粒细胞减少。他对停药和短期使用皮质类固醇有反应。如果要使用米诺环素，建议定期监测肝毒性。
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