Smith M M, Saunders G K, Payne J T, Cox C F
Comparative Oral Research Laboratory, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg 24061-0442, USA.
J Periodontol. 1998 Jul;69(7):798-805. doi: 10.1902/jop.1998.69.7.798.
Vital amputation of the mesio-buccal root of the maxillary fourth premolar (P4) was performed bilaterally in 8 dogs. Histopathologic evaluation of the tooth structure revealed normal pulp in the remaining mesio-buccal, mesio-palatal, and distal roots and crown during a mean follow-up period of 3.5 +/- 1.9 months. Amputation site healing was characterized by a reparative dentin bridge produced by odontoid cells. Tunnel defects were observed in 13 of 16 (81%) dentin bridges. It is concluded that the pulp of a tri-rooted, periodontal disease-free tooth remains viable during a 6-month period following vital root amputation. These results point to the intriguing possibility that this may also occur in humans, however, this needs to be directly tested in man.
对8只犬双侧进行上颌第四前磨牙（P4）近中颊根的活髓切断术。在平均3.5±1.9个月的随访期内，对牙齿结构进行组织病理学评估，结果显示剩余的近中颊根、近中腭根和远中根及牙冠中的牙髓正常。切断部位的愈合表现为成牙本质细胞产生的修复性牙本质桥。在16个牙本质桥中的13个（81%）观察到隧道状缺损。得出的结论是，在活髓切断术后6个月内，三根且无牙周疾病的牙齿的牙髓仍保持活力。这些结果表明，这种情况在人类中也可能发生，这一有趣的可能性值得关注，然而，这需要在人体中进行直接测试。
