Lecrubier Y
INSERM, Hôpital le Salpêtière, Paris, France.
J Clin Psychiatry. 1998;59 Suppl 8:11-4; discussion 15-6.
Panic disorder comorbid with other psychiatric conditions appears to be more common than panic disorder alone. Depression is the most frequently associated disorder. This article reviews the detrimental effects of comorbidity on the severity and course of panic disorder. The presence of comorbidity results in more severe anxiety and depressive symptoms, a higher rate of suicide attempts, a higher frequency of other comorbid conditions, and a poorer response and compliance to treatment. Thus, it is important for physicians to be aware of the possibility of comorbidity in patients with panic disorder in order to select the most appropriate therapy to target all components of their condition.
与其他精神疾病共病的惊恐障碍似乎比单纯的惊恐障碍更为常见。抑郁症是最常与之相关的疾病。本文综述了共病对惊恐障碍严重程度和病程的有害影响。共病的存在会导致更严重的焦虑和抑郁症状、更高的自杀未遂率、更高的其他共病发生率，以及对治疗的反应和依从性更差。因此，医生意识到惊恐障碍患者存在共病的可能性非常重要，以便选择最恰当的治疗方法来针对其病情的所有方面。
