Carbonell Sanchis R, Marcote Icart J, López Catalá F, Canals Ruiz P, Peris Beaufils J L, García Castell J
Hospital de Sangunto, Valencia.
Acta Otorrinolaringol Esp. 1998 May;49(4):313-6.
A case is reported of primary transitional-cell carcinoma in the frontal sinus of a 54-year-old woman, which was interesting because of the histological type, evolution, and difficulty of follow-up.
A 54-year-old woman with no history of exposure to risk factors presented swelling of the frontal area of 3 months duration. Fine needle aspiration biopsy revealed an adenoma but TAC showed an intrasinusal tumor with destruction of the inner and outer walls. Surgical exeresis revealed the correct histological diagnosis. Local recurrence at 12 months, without cervical lymph nodes or distant metastases, was treated surgically and the patient remained asymptomatic and disease-free 24 months later.
Malignant tumors of the frontal sinus are rare in the literature. We describe the histological features of transitional-cell tumor and emphasize its similarity with papilloma, benign behavior and management options, in which surgery is of choice. Prognostic and survival factors in the literature are reviewed.
报告一例54岁女性额窦原发性移行细胞癌病例，该病例因其组织学类型、病情发展及随访困难而颇具研究价值。
一名无危险因素暴露史的54岁女性，额部肿胀3个月。细针穿刺活检显示为腺瘤，但计算机断层扫描（TAC）显示鼻窦内肿瘤，内外壁均被破坏。手术切除后得出正确的组织学诊断。12个月时出现局部复发，无颈部淋巴结转移或远处转移，再次接受手术治疗，24个月后患者无症状且无疾病复发。
文献中额窦恶性肿瘤较为罕见。我们描述了移行细胞瘤的组织学特征，强调其与乳头状瘤的相似性、良性行为及治疗选择，其中手术为首选治疗方法。并对文献中的预后和生存因素进行了综述。
