Burde R M, Moore F J, Holmberg N
Ann Ophthalmol. 1976 Sep;8(9):1105-14.
The present study tested the assertion that there exists exclusively in persons with senile cataracts a serum factor capable of precipitating with gamma crystallin extract from bovine lens. The results of this work do not support this assertion without the imposition of rigid specifications regarding test solution concentrations and observation time. Among the 84 subjects tested, 2 individuals had posterior subcapsular cataracts. The precipitates resulting from incubation with serum from these individuals were similar to those resulting from incubations with serum from senile cataract patients. The present study did not confirm the existence of exclusive serum factors capable of precipitating with gamma crystallin extract in patients with senile cataracts.
本研究对一种说法进行了验证，即仅在老年性白内障患者体内存在一种血清因子，该因子能够与牛晶状体的γ-晶状体蛋白提取物发生沉淀反应。若不对测试溶液浓度和观察时间设定严格标准，本研究结果并不支持这一说法。在接受测试的84名受试者中，有2人患有后囊下白内障。这些个体的血清孵育产生的沉淀物与老年性白内障患者血清孵育产生的沉淀物相似。本研究未证实老年性白内障患者体内存在能与γ-晶状体蛋白提取物发生沉淀反应的特异性血清因子。
