Crescenzo D G, Shabahang M, Garvin D, Evans S R
Department of Surgery, Georgetown University Medical Center, Washington, DC, USA.
Thyroid. 1998 Jul;8(7):597-9. doi: 10.1089/thy.1998.8.597.
Parathyroid carcinoma is a rare clinical entity with a reported incidence of between 0.5% and 4% of all patients with primary hyperparathyroidism. Equally as unusual is the presence of an intrathyroidal parathyroid gland, which is usually found at the time of exploration by exclusion after extensive dissection has been performed in the usual anatomic locations for the parathyroid glands. This is the description of a case of intrathyroidal parathyroid cancer that presented as primary hyperparathyroidism with a left neck mass. On exploration, an enlarged left lobe of the thyroid was present and no left superior pole parathyroid gland was found with exploration. A left thyroid lobectomy was performed that confirmed a parathyroid cancer that was entirely intrathyroidal. This is the first known reported case in the literature of a carcinoma arising within the thyroid gland.
甲状旁腺癌是一种罕见的临床实体，据报道在所有原发性甲状旁腺功能亢进患者中的发病率为0.5%至4%。同样不常见的是甲状腺内甲状旁腺的存在，通常是在对甲状旁腺的常规解剖位置进行广泛解剖后通过排除法在探查时发现的。本文描述了一例甲状腺内甲状旁腺癌病例，该病例表现为原发性甲状旁腺功能亢进并伴有左颈部肿块。探查时，发现甲状腺左叶肿大，未发现左上极甲状旁腺。实施了左甲状腺叶切除术，证实为完全位于甲状腺内的甲状旁腺癌。这是文献中已知的首例起源于甲状腺内的癌的报道病例。
