Fleming A, Crown J M, Corbett M
Ann Rheum Dis. 1976 Aug;35(4):357-60. doi: 10.1136/ard.35.4.357.
We describe features with onset in 102 patients seen within the first year of rheumatoid disease. The male:female ratio was approximately 3:4, suggesting a near equal sex incidence at onset. The disease started more often in the colder months and was usually insodious, symmetrical, and involved the upper limbs. The patients were followed prospectively and outcome was assessed after a mean of 4.5 years. Older patients fared worse and there was a trend for a poorer prognosis to be indicated by an insidious onset and early progression to symmetrical involvement.
我们描述了类风湿病发病第一年就诊的102例患者的特征。男女比例约为3:4,提示发病时性别发病率近乎相等。疾病更常始于较寒冷的月份,通常隐匿、对称,且累及上肢。对患者进行前瞻性随访,平均4.5年后评估预后。年龄较大的患者病情较差,隐匿起病且早期进展为对称性受累提示预后较差。