Schnegg A, Kirchgessner M
Arch Tierernahr. 1976 Aug;26(8):543-9. doi: 10.1080/17450397609426724.
Studies were carried out investigating the role of nickel as an essential element in the growth of rats. Reduced levels of iron, copper and zinc were found in the liver, spleen and kidneys during Ni deficiency. These findings could be reproduced in 2 generations of 30-day and 50-day-old rats. Reduced rates of Fe storage during Ni deficiency were, in some cases, even noted of the Fe supply was raised to a level of as high as 100 mg Fe per kg of the diet. This accounted for the diminished haemoglobin values, the reduced erythrocyte count and reduced hematocrite found under conditions of Ni deficiency.
开展了多项研究来调查镍作为大鼠生长必需元素的作用。在镍缺乏期间，肝脏、脾脏和肾脏中铁、铜和锌的水平降低。这些发现可以在两代30日龄和50日龄的大鼠中重现。在某些情况下，即使将铁的供应量提高到每千克饮食100毫克铁的水平，镍缺乏期间铁的储存率仍会降低。这解释了在镍缺乏条件下发现的血红蛋白值降低、红细胞计数减少和血细胞比容降低的原因。
