Brown O R, Hines M B
Aviat Space Environ Med. 1976 Sep;47(9):954-7.
Continuous and interval exposures to 1 atmosphere of oxygen (hyperoxia) were examined using insects. Hyperoxia did not affect hatchability of Heliothis zea or Trichoplusia ni. Continuous hyperoxia was 100% lethal for H. zeal and T. ni. Most insects died as larvae and pupae of H. zea which resulted were deformed, reduced in weight, and failed to emerge. Hyperoxic exposures of T. ni for 48 h at sequential 48-h intervals during development, revealed that first instar and prepupae were most sensitive to hyperoxia and 80% were killed when exposed to only 24 h of hyperoxia as prepupae. T. ni which survived hyperoxia exposures at all development stages tested, were capable of producing progeny. The differential hyperoxic sensitivity and its correlation with specific morphogenetic stages suggest the usefulness of these insect species for studying biochemical sites of oxygen toxicity.
使用昆虫研究了持续和间歇性暴露于1个大气压的氧气（高氧环境）的情况。高氧环境不影响棉铃虫或粉纹夜蛾的孵化率。持续高氧环境对棉铃虫和粉纹夜蛾具有100%的致死率。大多数棉铃虫在幼虫和蛹期死亡，所产生的棉铃虫幼虫畸形、体重减轻且无法羽化。在粉纹夜蛾发育过程中，以连续48小时的间隔进行48小时的高氧暴露，结果显示，一龄幼虫和预蛹对高氧最为敏感，仅在预蛹期暴露于24小时高氧环境时，80%的粉纹夜蛾会死亡。在所有测试发育阶段经高氧暴露存活下来的粉纹夜蛾能够产生后代。高氧敏感性差异及其与特定形态发生阶段的相关性表明，这些昆虫物种对于研究氧毒性的生化位点具有实用性。
