人类针对产肠毒素大肠杆菌菌毛表面抗原6的抗体反应。
Antibody responses in humans against coli surface antigen 6 of enterotoxigenic Escherichia coli.
作者信息
Helander A, Wennerås C, Qadri F, Svennerholm A M
机构信息
Department of Medical Microbiology and Immunology, Göteborg University, Göteborg, Sweden.
出版信息
Infect Immun. 1998 Sep;66(9):4507-10. doi: 10.1128/IAI.66.9.4507-4510.1998.
Abstract
Enterotoxigenic Escherichia coli (ETEC) strains expressing only coli surface antigen 6 (CS6) have previously been isolated from patients with diarrhea, but the immunogenicity of CS6 has not been established in humans. We have detected CS6-specific immunoglobulin A responses in the feces and blood of patients convalescing from natural ETEC disease and of volunteers given an oral ETEC vaccine.
摘要
此前已从腹泻患者中分离出仅表达大肠杆菌表面抗原6（CS6）的产肠毒素大肠杆菌（ETEC）菌株，但CS6在人体中的免疫原性尚未明确。我们在自然感染ETEC疾病后正在康复的患者以及口服ETEC疫苗的志愿者的粪便和血液中检测到了CS6特异性免疫球蛋白A反应。
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