Iotti A, Elsner B, Avagnina A, Iotti R, Debonis D
Servicio de Patología, CEMIC, Buenos Aires, Argentina.
Medicina (B Aires). 1998;58(3):298-300.
We report the case of a 39 years old man who presented with a rapidly enlarging, painless mass in his left side of the neck. The mass was excised and turned out to be a lymph node. Histologically, it showed a proliferation of oval to spindle cells growing in sheets and fascicles, occasionally forming a storiform pattern. Tumor cells showed large nuclei, dispersed chromatin and small evident nucleoli. Neoplastic cells were positive for immunohistochemical markers vimentin, CD 68, CD 21, CD 35 and R 4/23. Ultrastructural examination showed long cytoplasmatic processes joined by desmosomes. The patient was treated with local radiotherapy and is alive and well 18 months after the excision. Follicular dendritic cell sarcoma is a very unusual tumor that merits wider recognition.
我们报告了一例39岁男性患者，其左侧颈部出现一个迅速增大的无痛性肿块。该肿块被切除，结果是一个淋巴结。组织学上，它显示出椭圆形至梭形细胞呈片状和束状生长的增殖，偶尔形成席纹状模式。肿瘤细胞显示细胞核大、染色质分散且核仁小而明显。肿瘤细胞对免疫组化标志物波形蛋白、CD 68、CD 21、CD 35和R 4/23呈阳性。超微结构检查显示长的细胞质突起通过桥粒相连。患者接受了局部放疗，切除后18个月仍存活且状况良好。滤泡树突状细胞肉瘤是一种非常罕见的肿瘤，值得更广泛的认识。
