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[无创机械通气治疗HIV阳性患者的重症肺炎]

[Non-invasive mechanical ventilation as treatment for severe pneumonia in an HIV positive patient].

作者信息

Sobrino E M, Montiel G C, Quadrelli S A, Fishman D, Roncoroni A J

机构信息

Instituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 1998;58(3):303-6.

PMID:9713103
Abstract

A 27 year-old HIV+ patient was admitted to the hospital for probable Pneumocystis carinii pneumonia (PCP). He was severely dyspneic, with respiratory rate of 44 x min and accessory respiratory muscle contraction. The alveolar-arterial quotient was 0.35. Ventilation by BiPAP was applied during 12 hours. After BiPAP a/AO2 was O.42, with amelioration of dyspnea, decrease of respiratory rate (25 x min) and without using of accessory respiratory muscles. No complications occurred. At the end of hospital stay a/AO2 was 0.68. CPAP application but not BiPAP has been reported in PCP. Our patient showed evident improvement after BiPAP, suggesting that this method of ventilation is useful and should be incorporated to the routine management of these patients.

摘要

一名27岁的HIV阳性患者因疑似卡氏肺孢子虫肺炎(PCP)入院。他严重呼吸困难,呼吸频率为44次/分钟,伴有辅助呼吸肌收缩。肺泡-动脉氧分压差为0.35。应用双水平气道正压通气(BiPAP)12小时。BiPAP治疗后,动脉血氧分压/肺泡氧分压(a/AO2)为0.42,呼吸困难改善,呼吸频率降低(25次/分钟),且不再使用辅助呼吸肌。未发生并发症。住院结束时,a/AO2为0.68。据报道,PCP患者应用持续气道正压通气(CPAP)而非BiPAP。我们的患者在BiPAP治疗后显示出明显改善,表明这种通气方法是有用的,应纳入这些患者的常规管理中。

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