Hepatic cholesterol-7alpha-hydroxylase activity in neurogenic hypercholesterolemia.
作者信息
St George S, Friedman M, Byers S O, Neuman R
出版信息
Atherosclerosis. 1976 Sep;24(3):387-92. doi: 10.1016/0021-9150(76)90131-3.
PMID:971342
Abstract
The cholesterol-7alpha-hydroxylase activity of hepatic microsomal preparations of hypothalamic hypercholesterolemic rats and normal rats was assayed in rats fed diets high and low in cholesterol, and in rats killed at the supposed height and at the nadir of the diurnal cycle of enzyme activity. The activity of this enzyme system appeared to be unimpaired in the hypothalamic hypercholesterolemic rat.
摘要
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