Meza G
Departamento de Neurociencias, Universidad Nacional Autónoma de México, D.F. Mexico.
Neurobiology (Bp). 1998;6(1):109-25.
The main criteria asked to a GABAergic synapse, have been fulfilled by GABA at the recepto-neural junction of the sensory periphery of vestibular organs in vertebrates. These criteria include the demonstration of its precursor, its synthesizing and degrading (inactivating) mechanisms and their localization with the right polarity of a GABAergic synapse. A novel GABA depolarizing action with particular pharmacological characteristics and expression of subunits of GABA receptors of the synaptic type (GABAA, GABAB or a putative mixed GABAA-GABAC) that could account for these properties are discussed.
对GABA能突触提出的主要标准，已被脊椎动物前庭器官感觉外周的受体 - 神经连接处的GABA所满足。这些标准包括其前体的证明、其合成和降解（失活）机制及其在具有正确极性的GABA能突触中的定位。本文讨论了一种具有特殊药理学特性的新型GABA去极化作用，以及可能解释这些特性的突触型GABA受体（GABAA、GABAB或假定的混合GABAA - GABAC）亚基的表达。
