Muramatsu T, Hatoko M, Shirai T, Vanittanakom P
Department of Dermatology, Nara Medical University, Japan.
J Dermatol. 1998 Jul;25(7):443-7. doi: 10.1111/j.1346-8138.1998.tb02432.x.
The patient was a 15-year-old male. Since birth, he has suffered from recurrent blistering, especially on the extremities. Histology and electron microscopic finding of the cutaneous lesions were compatible with those of dystrophic epidermolysis bullosa. Contracture and mobility limitation of the hands had gradually deteriorated. Prior to the admission to our clinic, both hands' contracture had been surgically treated 4 times in another hospital; however, after treatment with skin grafting, hand contracture recurred each time within one year. This time, surgical treatment was carried out for his left hand contracture using an abdominal skin flap under local anesthesia. In comparison with the free skin graft the abdominal skin flap improved hand contracture for a longer time. Abdominal skin flap is recommended as a method for the treatment of hand contracture of patients with dystrophic epidermolysis bullosa.
该患者为一名15岁男性。自出生以来，他一直反复出现水疱，尤其是在四肢。皮肤病变的组织学和电子显微镜检查结果与营养不良性大疱性表皮松解症相符。手部的挛缩和活动受限逐渐恶化。在入住我们诊所之前，双手挛缩已在另一家医院接受了4次手术治疗；然而，每次皮肤移植治疗后，手部挛缩在一年内都会复发。此次，在局部麻醉下使用腹部皮瓣对其左手挛缩进行了手术治疗。与游离皮肤移植相比，腹部皮瓣改善手部挛缩的时间更长。建议将腹部皮瓣作为治疗营养不良性大疱性表皮松解症患者手部挛缩的一种方法。
