Eriguchi N, Aoyagi S, Hara M, Miyazaki T, Tanaka E, Hashimoto M
Department of Surgery, Kurume University School of Medicine, Japan.
Kurume Med J. 1998;45(2):231-4. doi: 10.2739/kurumemedj.45.231.
Pseudomyxoma peritonei is a disease characterized by the progressive accumulation of mucinous ascites within the abdomen and pelvis. Metastatic disease outside the peritoneal cavity is unusual. Gastrointestinal function is lost from external compression of stomach, small bowel, and large bowel. We present three cases of pseudomyxoma peritonei which were treated by different therapeutic methods. Case 1 was a 61-year-old man who underwent treatment by appendectomy with administration of Cisplatin and Doxorubicin hydrochloride into the intraperitoneal cavity. Case 2 was a 64-year-old woman who underwent bilateral oophorectomy with administration of Cisplatin and ADM into the intraperitoneal cavity. About 4 years after the first operation, she died of peritonitis due to small and large bowel perforations underlying recurrent tumors. Case 3 was a 79-year-old woman who underwent surgery to evacuate about 4000 ml of mucinous ascites, and received intraperitoneal administration of 5-Fluorouracil (500 mg/day) for 5 days without severe complications.
腹膜假黏液瘤是一种以腹腔和盆腔内黏液性腹水进行性积聚为特征的疾病。腹腔外转移性疾病并不常见。胃肠道功能因胃、小肠和大肠受到外部压迫而丧失。我们报告三例腹膜假黏液瘤患者，采用了不同的治疗方法。病例1是一名61岁男性，接受了阑尾切除术，并向腹腔内注射顺铂和盐酸多柔比星进行治疗。病例2是一名64岁女性，接受了双侧卵巢切除术，并向腹腔内注射顺铂和阿霉素。首次手术后约4年，她因复发性肿瘤导致小肠和大肠穿孔引起的腹膜炎而死亡。病例3是一名79岁女性，接受了手术以排出约4000毫升黏液性腹水，并接受了5天的腹腔内注射5-氟尿嘧啶（500毫克/天），未出现严重并发症。
