巴氏涂片检查中子宫内膜细胞与子宫内膜癌之间的相关性。
Correlation between endometrial cells on Papanicolaou smear and endometrial carcinoma.
作者信息
Kerpsack J T, Finan M A, Kline R C
机构信息
Department of Obstetrics and Gynecology, Ochsner Clinic, New Orleans, La., USA.
出版信息
South Med J. 1998 Aug;91(8):749-52. doi: 10.1097/00007611-199808000-00009.
BACKGROUND
A retrospective study was done to assess the correlation between endometrial cells on routine cervical cytology and carcinoma of the endometrium.
METHODS
In a 4-year period, endometrial cells of some type were identified on the Papanicolaou (Pap) smears of 61 women, of whom 52 had further diagnostic evaluation of the endometrium. Data were analyzed with a multivariate stepwise logistic regression.
RESULTS
The results indicated an association of endometrial cells in Pap smears with carcinoma of the endometrium in seven patients (13.5%). In 45 patients (86.5%), the final diagnosis was benign. Factors that impacted the diagnosis of carcinoma were the findings of atypical or cancerous endometrial cells on Pap smear and abnormal vaginal bleeding.
CONCLUSIONS
These data indicate the importance of further diagnostic evaluation with endometrial sampling in postmenopausal patients with endometrial cells seen in Pap smears, especially those with abnormal bleeding.
背景
开展一项回顾性研究以评估常规宫颈细胞学检查中的子宫内膜细胞与子宫内膜癌之间的相关性。
方法
在4年期间，在61名女性的巴氏涂片上发现了某种类型的子宫内膜细胞，其中52名对子宫内膜进行了进一步的诊断评估。采用多变量逐步逻辑回归分析数据。
结果
结果表明，7名患者（13.5%）的巴氏涂片中子宫内膜细胞与子宫内膜癌有关联。45名患者（86.5%）最终诊断为良性。影响癌症诊断的因素是巴氏涂片上发现非典型或癌性子宫内膜细胞以及异常阴道出血。
结论
这些数据表明，对于巴氏涂片检查中发现有子宫内膜细胞的绝经后患者，尤其是有异常出血的患者，进行子宫内膜取样进一步诊断评估具有重要意义。
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