Chaudhari L S, Kane D G, Shivkumar B, Kamath S K
Department of Anaesthesiology, KEM Hospital & Seth GS Medical College, Parel, Mumbai.
J Postgrad Med. 1996 Apr-Jun;42(2):43-5.
100 patients with ASA risk I & II and undergoing perianal surgery were studied for anaesthetic effects and postoperative analgesia following either intrathecal pethidine or lignocaine. Saddle block was performed either with intrathecal pethidine 5% (50 mg/ml) 0.5 mg/kg or 1 ml of 5% lignocaine. Sensory and motor block postoperative analgesia, need for additional analgesia were studied. The onset of sensory and motor blockade with lignocaine was faster than pethidine. However the sensory and motor blockade lasted longer with pethidine. The duration of postoperative analgesia was 15.39 +/- 5.14 hours as against duration of postoperative analgesia with lignocaine which was 1.3 +/- 0.53 hours. Only 10% of patients in the pethidine group required intramuscular analgesic supplementation whereas 30% of patients in the lignocaine group required intramuscular analgesic supplementation.
对100例美国麻醉医师协会（ASA）分级为I级和II级且正在接受肛周手术的患者进行了研究，观察鞘内注射哌替啶或利多卡因后的麻醉效果和术后镇痛情况。鞍区阻滞采用鞘内注射5%（50mg/ml）哌替啶0.5mg/kg或1ml 5%利多卡因进行。对感觉和运动阻滞、术后镇痛以及额外镇痛需求进行了研究。利多卡因引起感觉和运动阻滞的起效时间比哌替啶快。然而，哌替啶引起的感觉和运动阻滞持续时间更长。哌替啶组术后镇痛持续时间为15.39±5.14小时，而利多卡因组术后镇痛持续时间为1.3±0.53小时。哌替啶组仅10%的患者需要肌内补充镇痛药物，而利多卡因组30%的患者需要肌内补充镇痛药物。
