Sahu S, Raipancholia R, Pardiwalla F K, Pathare A V
Department of Dr J C Patel Hematology, KEM Hospital, Parel, Mumbai.
J Postgrad Med. 1996 Jul-Sep;42(3):88-90.
An 82 year old man developed antibodies against coagulation factor VIII:C without any apparent cause. Bleeding from the soft tissue cavity could not be controlled by factor VIII:C concentrates, immunosuppression with steroids and intravenous immunoglobulin therapy in the standard dosages. However, a single injection of Epsilon Aminocaproic Acid (EACA) instilled into the cavity under aseptic precautions achieved lasting hemostasis with resultant wound healing.