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急性心肌梗死患者冠状动脉支架置入术后的医院结局

Hospital outcome after bailout coronary stenting in patients with acute myocardial infarction.

作者信息

Himbert D, Juliard J M, Benamer H, Feldman L J, Aubry P, Steg P G

机构信息

Department of Cardiology, University Hospital Bichat, Paris, France.

出版信息

Cathet Cardiovasc Diagn. 1998 Aug;44(4):371-7. doi: 10.1002/(sici)1097-0304(199808)44:4<371::aid-ccd1>3.0.co;2-1.

Abstract

We evaluated the outcome of bailout coronary stenting in acute myocardial infarction. Fifty patients (35 men, mean age 60 plusmn; 12) with acute myocardial infarction consecutively underwent bailout stenting after primary and rescue coronary angioplasty (n=41 and 9, respectively). Cardiogenic shock was present in six patients, and 17 others had contraindications to thrombolysis. Stent implantation was successful in 49/50 patients. The antithrombotic regimen combined heparin, aspirin, and ticlopidine. One patient had symptomatic stent closure. Predischarge angiography in 41/44 survivors showed widely patent stents in 40/41 patients. Six patients (4 of whom had been admitted with cardiogenic shock) died in the hospital. During acute myocardial infarction, bailout stenting can achieve high TIMI grade 3 coronary patency (here, 92%), and low acute stent closure rates (here, 2%). However, in-hospital mortality remained high, at nearly 10%, mainly due to the severe risk profile in this patient subset.

摘要

我们评估了急性心肌梗死患者补救性冠状动脉支架置入术的效果。50例急性心肌梗死患者(35例男性,平均年龄60±12岁)在分别接受了初次及补救性冠状动脉血管成形术(分别为41例和9例)后连续接受了补救性支架置入术。6例患者出现心源性休克,另外17例有溶栓禁忌证。49/50例患者支架植入成功。抗血栓治疗方案联合应用肝素、阿司匹林和噻氯匹定。1例患者出现有症状的支架闭塞。41/44例存活患者出院前血管造影显示,40/41例患者支架通畅。6例患者(其中4例入院时伴有心源性休克)在医院死亡。在急性心肌梗死期间,补救性支架置入术可实现较高的TIMI 3级冠状动脉通畅率(此处为92%)和较低的急性支架闭塞率(此处为2%)。然而,住院死亡率仍高达近10%,主要是由于该患者亚组的风险状况严重。

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