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过去十年间冠状动脉成形术、搭桥手术及保守疗法在冠状动脉疾病治疗中的应用。

Use of coronary angioplasty, bypass surgery, and conservative therapy for treatment of coronary artery disease over the past decade.

作者信息

Delacrétaz E, Meier B

机构信息

Division of Cardiology, University Hospital, Bern, Switzerland.

出版信息

Eur Heart J. 1998 Jul;19(7):1042-6. doi: 10.1053/euhj.1997.0801.

DOI:10.1053/euhj.1997.0801
PMID:9717039
Abstract

AIMS

There is a continuous increase in the number of percutaneous transluminal coronary angioplasty procedures performed per year per population in most industrialised countries. This analysis searches for trends in treatment decisions after diagnostic coronary angiography.

METHODS AND RESULTS

The degree of coronary artery disease and the therapeutic strategy were determined retrospectively in consecutive patients undergoing coronary angiography at a Swiss university hospital during three different time periods in the past 11 years (n = 750 in 1994, n = 500 in 1990, and n = 545 in 1983). The indication for coronary angioplasty rose from 45% in 1983 to 78% in 1990 and 87% in 1994 in patients with one-vessel disease, from 25% to 38% and 71% in patients with two-vessel disease, and from 10% to 24% and 29% in patients with three-vessel disease. In contrast, the use of conservative therapy declined with time, independent of the severity of coronary artery disease. Indications for coronary artery bypass grafting decreased in patients with two-vessel disease, but did not change in patients with three-vessel disease over the 11 year period.

CONCLUSIONS

The use of coronary angioplasty, bypass surgery, and conservative therapy changed drastically over the past decade, with an increasing use of angioplasty and a multivessel disease, and of bypass surgery in two-vessel disease. The expansion of coronary angioplasty is mainly related to increased use in patients previously treated conservatively.

摘要

目的

在大多数工业化国家,每年每单位人口进行的经皮腔内冠状动脉成形术的数量持续增加。本分析旨在探寻诊断性冠状动脉造影术后治疗决策的趋势。

方法与结果

回顾性确定过去11年中三个不同时间段在瑞士一家大学医院连续接受冠状动脉造影的患者的冠状动脉疾病程度和治疗策略(1994年n = 750例,1990年n = 500例,1983年n = 545例)。单支血管病变患者中,冠状动脉成形术的适应证从1983年的45%升至1990年的78%和1994年的87%;双支血管病变患者中,从25%升至38%和71%;三支血管病变患者中,从10%升至24%和29%。相比之下,保守治疗的使用随时间减少,与冠状动脉疾病的严重程度无关。双支血管病变患者冠状动脉旁路移植术的适应证减少,但在11年期间三支血管病变患者的适应证未变。

结论

在过去十年中,冠状动脉成形术、搭桥手术和保守治疗的使用发生了巨大变化,血管成形术在多支血管病变中的使用增加,搭桥手术在双支血管病变中的使用增加。冠状动脉成形术的扩大主要与以前接受保守治疗的患者使用增加有关。

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