Rodríguez Fernández A, Solís Sánchez G, Ballesteros García S, Llaneza Ruiz J, Lagunilla Herrero L, Pérez Méndez C
Sección Neonatología del Servicio de Pediatría, Hospital de Cabueñes (INSALUD), Gijón.
An Esp Pediatr. 1998 Jul;49(1):55-9.
The purpose of this study was to determine the number of skin punctures and volume of blood removed for analytical purposes and the number and volume of red blood cell transfusions performed in premature neonates.
A case-control study was performed with a retrospective review of clinical records. Data about blood samples was gathered from the nursery forms and descriptive statistics were performed. Neonates less than 37 weeks gestational age, born in our hospital between 1/1/1992 and 12/31/1996, were studied. They were divided into two groups: Group 1) Those neonates receiving red blood cell transfusions; and Group 2) The control groups, which was comprised of the next premature baby born after each infant who underwent transfusion.
There were 419 premature infants out of 9,635 live newborns (4.3%). Of the 419 premature infants, 123 (29.3%) underwent transfusion therapy. The study groups after exclusions were comprised of 105 infants in groups 1 and 105 infants in the control group, or group 2. The average number of blood samples was 5.4 per infant (range 0-37). The mean volume of blood removed was 26.3 cc per infant (range 0-167 cc) or 15.1 cc/kg (birthweight). The total number of transfusions was 187, with a mean of 1.8 per infant (range 1-12). The mean volume transfused was 43.1 cc per infant (range 20-146 cc). The number of blood samples, total volume of blood removed and percentage of blood volume removed were significantly higher in the transfusion group than in the control group.
The number and volume of blood samples in our premature infants are excessive. We should reduce both to minimize the need of red blood cell transfusions and the associated risks.
本研究旨在确定用于分析目的的皮肤穿刺次数和采血量，以及早产儿进行红细胞输血的次数和输血量。
进行了一项病例对照研究，对临床记录进行回顾性分析。从保育记录表格中收集有关血样的数据，并进行描述性统计。研究对象为1992年1月1日至1996年12月31日在我院出生的孕周小于37周的新生儿。他们被分为两组：第1组）接受红细胞输血的新生儿；第2组）对照组，由每组接受输血的婴儿之后出生的下一个早产儿组成。
9635例活产新生儿中有419例早产儿（4.3%）。在这419例早产儿中，123例（29.3%）接受了输血治疗。排除后，研究组第1组有105例婴儿，对照组（第2组）有105例婴儿。每名婴儿的血样平均采集次数为5.4次（范围0 - 37次）。平均采血量为每名婴儿26.3毫升（范围0 - 167毫升）或15.1毫升/千克（出生体重）。输血总数为187次，每名婴儿平均输血1.8次（范围1 - 12次）。平均输血量为每名婴儿43.1毫升（范围20 - 146毫升）。输血组的血样采集次数、总采血量和采血占血量的百分比均显著高于对照组。
我们的早产儿血样采集次数和采血量过多。我们应减少两者，以尽量减少红细胞输血需求及相关风险。
