Casadei R, Greggi T, Miglietta A, Perozzi M, Barchetti M, Parisini P
Divisione di Chirurgia Vertebrale, Istituto Ortopedico Rizzoli, Bologna.
Chir Organi Mov. 1998 Jan-Jun;83(1-2):149-58.
A total of 25 pathologic fractures in patients affected with thoracolumbar vertebral metastases associated with neurologic deficit are reported. None of the pathologic fractures were stable, while 14 were unstable and 11 were very unstable. Decompression with intralesional excision of the neoplastic mass compressing the dural sac was performed in all of the cases. Posterior stabilization was performed in the first cases using systems of sublaminar segmental fixation, and thereafter using systems of pedicle fixation. Removal of the vertebral body followed by anterior fusion after preventive posterior stabilization was performed in 2 cases. Pain symptoms regressed in 85% of the cases and in more than 50% of the patients there was improvement in the neurologic findings and in vertebral deformity consequent to fracture. Mean survival rate was 12 months. Despite the limited number of cases posterior stabilization of pathological fractures is a good choice of treatment in patients with severe neurologic deficit.
本文报告了25例患有胸腰椎椎体转移瘤并伴有神经功能缺损的患者发生的病理性骨折。所有病理性骨折均不稳定,其中14例为不稳定型,11例为极不稳定型。所有病例均行肿瘤块切除减压术,以解除对硬脊膜囊的压迫。首例采用椎板下节段固定系统进行后路稳定手术,其后采用椎弓根固定系统。2例行预防性后路稳定手术后,切除椎体并进行前路融合。85%的病例疼痛症状缓解,超过50%的患者神经功能及骨折所致椎体畸形得到改善。平均生存率为12个月。尽管病例数量有限,但对于神经功能严重缺损的患者,病理性骨折的后路稳定手术仍是一种较好的治疗选择。