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术中脊髓造影在胸腰椎骨折治疗中的应用

[Intra-operative myelography in treatment of fractures of thoracolumbar spine].

作者信息

Tomčovčík L, Cuha R, Raši R

机构信息

Klinika úrazovej chirurgie FNsP J. A. Reimana a FZ PU, Prešov.

出版信息

Acta Chir Orthop Traumatol Cech. 2010 Aug;77(4):320-6.

PMID:21059330
Abstract

PURPOSE OF THE STUDY

The aim of this retrospective study was to evaluate the results of intra-operative myelography as the method used to assess the reduction of bone fragments from the posterior margin of the vertebral body.

MATERIAL AND METHODS

Forty patients with 42 comminuted fractures of the thoracolumbar spine were included in the study. The pre-operative spinal stenosis caused by bone fragments from the posterior margin of the vertebral body, as detected by CT scanning, ranged from 25 % to 85 %. Neurological deficit was due to injury in 19 patients and in one it developed post-operatively after the patient stood and walked. After ligamentotaxis and internal fixation, intra-operative myelography was used to show decompression of the spinal canal. A spinal block or severe constriction of contrast flow was an indication for hemilaminectomy (laminectomy) and direct decompression of the spinal canal. In the patients with neurological deficit and severe spinal stenosis persisting after ligamentotaxis and detectable by skiascopy, hemilaminectomy (laminectomy) and direct spinal decompression followed by intra-operative myelography were carried out.

RESULTS

Intra-operative myelography was used 46 -times (20-times in 20 patients free from neurological deficit and 26-times in 20 patients with neurological deficit). In 38 cases (82.6 %) dural sac compression was not present (patients with neurological deficit, 13-times after ligamentotaxis, eight-times after ligamentotaxis and hemilaminectomy with direct decompression, twi- ce at repeat surgeryúúú patients without neurological deficit, 15-times). On two occasions (4.4 %) the contrast agent injected into the dural sac did not make the interior body part visible, on three occasions (6.5 %) contrast medium was injected extradurally, and dural sac compression following ligamentotaxis requiring hemilaminectomy (laminectomy) and direct decompression occurred in three cases (6.5 %). In the patients without neurological deficit, dural sac compression was not recorded. No serious complications associated with contrast medium injection in the dural sac were present, and there was no deterioration of neurological symptoms due to a dural tap. In three cases (6.5 %) a false negative finding was recorded, showing free flow of contrast medium with no areas of constriction or obstruction and signs of post-operative nerve irritation ( radicular syndrome associated with L3 fracture with a fragment placed laterally in two patients and hyperalgesia of the thigh after T12 fracture in one patient). Repeat surgery and additional decompression (hemilaminectomy and foraminotomy, laminectomy) resulted in immediate resolution of neurological symptoms.

DISCUSSION

The success rate, complications and disadvantages of intra-operative myelography have not been reported. At present, ionic water-soluble contrast agents used for intrathecal administration are associated with only a low number of serious complications. Neurological deficit due to dural tap is rare. Extradural administration is not effective. A disadvantage reported here involves a failure to visualize the area because of a low amount of contrast agent administered to avoid spinal cord injury. A possibility of false negative findings arising from only one lateral view of the contrast agent flowing round fragments is the major disadvantage. In contrast to the previous reports, we relate the false negative findings to neurological findings.

CONCLUSIONS

Intra-operative myelography is still a currently used method. Its advantages include a simple procedure without removal of posterior column structures, and the possibility of objective recording and continuous observation of the dural sac. The free flow of contrast medium makes obstruction of the spinal canal impossible. The consequences of a false negative finding can be successfully treated at the second stage.

摘要

研究目的

本回顾性研究旨在评估术中脊髓造影作为评估椎体后缘骨块复位方法的效果。

材料与方法

本研究纳入了40例患者,共42处胸腰椎粉碎性骨折。术前通过CT扫描检测到椎体后缘骨块导致的椎管狭窄程度为25%至85%。19例患者存在神经功能缺损是由于损伤所致,1例患者在站立行走后出现术后神经功能缺损。在进行韧带整复和内固定后,采用术中脊髓造影来显示椎管减压情况。脊髓阻滞或造影剂流动严重受限提示需行半椎板切除术(椎板切除术)并直接减压椎管。对于韧带整复后仍存在神经功能缺损且通过X线透视可检测到严重椎管狭窄的患者,先进行半椎板切除术(椎板切除术)和直接脊髓减压,然后进行术中脊髓造影。

结果

术中脊髓造影共使用46次(20例无神经功能缺损患者使用20次,20例有神经功能缺损患者使用26次)。38例(82.6%)不存在硬脊膜囊受压情况(有神经功能缺损患者,韧带整复后13次,韧带整复及半椎板切除术并直接减压后8次,再次手术2次;无神经功能缺损患者,15次)。有2次(4.4%)注入硬脊膜囊的造影剂未能使体内部分显影,3次(6.5%)造影剂注入硬膜外,韧带整复后需要半椎板切除术(椎板切除术)并直接减压的硬脊膜囊受压情况有3例(6.5%)。在无神经功能缺损的患者中,未记录到硬脊膜囊受压情况。未出现与向硬脊膜囊内注入造影剂相关的严重并发症,也没有因硬脊膜穿刺导致神经症状恶化的情况。有3例(6.5%)出现假阴性结果,显示造影剂自由流动,无狭窄或阻塞区域,且无术后神经刺激体征(2例L3骨折碎片位于外侧的患者出现与神经根综合征相关的情况,1例T12骨折患者术后出现大腿痛觉过敏)。再次手术及额外减压(半椎板切除术和椎间孔切开术、椎板切除术)后神经症状立即缓解。

讨论

术中脊髓造影的成功率、并发症及缺点此前尚未见报道。目前,用于鞘内注射的离子型水溶性造影剂仅与少量严重并发症相关。因硬脊膜穿刺导致神经功能缺损的情况罕见。硬膜外注射无效。此处报道的一个缺点是,为避免脊髓损伤而注入的造影剂剂量过少,导致无法观察到相应区域。造影剂仅从一个侧位观察其围绕骨块流动,可能产生假阴性结果,这是主要缺点。与之前的报道不同,我们将假阴性结果与神经学检查结果相关联。

结论

术中脊髓造影仍是目前使用的一种方法。其优点包括操作简单,无需切除后柱结构,且能够客观记录和持续观察硬脊膜囊。造影剂的自由流动使椎管阻塞不可能发生。假阴性结果的后果在第二阶段可成功处理。

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