Iannarone C, Caratozzolo M, Costamagna L, Fegiz A, Tellan G, Baumgartner I, Maselli A M, Fantera A
Università degli Studi La Sapienza, Roma, Italy.
Eur Rev Med Pharmacol Sci. 1997 Nov-Dec;1(6):217-21.
Therapeutic ethanol injection into primitive or secondary hepatic tumours if performed in "one shot" causes a great deal of pain. For this reason an analgesic/sedation protocol was devised. This relies on the administration of ketorolac-propofol-nitrogen oxide mixture that has been used to treat patients with neoplastic hepatic diseases. A 20 patient series is described. Analgesic protocol was very effective and the only drawbacks were a residual sleepiness than in part is probably dependent on ethanol emigration into the bloodstream and consequently to the central nervous system depression.
一次性向原发性或继发性肝肿瘤内注射治疗性乙醇会引起剧烈疼痛。因此，设计了一种镇痛/镇静方案。该方案依赖于使用酮咯酸-丙泊酚-氧化亚氮混合物来治疗患有肝脏肿瘤疾病的患者。本文描述了一个20例患者的系列。镇痛方案非常有效，唯一的缺点是存在残余嗜睡，部分原因可能是乙醇进入血液，进而导致中枢神经系统抑制。
