DeGroff C G, Baptista A M, Sahn D J
Cardiovascular Flow Dynamics Research Laboratory, University of Colorado Health Science Center, The Children's Hospital, Denver 80218, USA.
J Am Soc Echocardiogr. 1998 Aug;11(8):809-18. doi: 10.1016/s0894-7317(98)70056-2.
Through numerical experimentation we investigated the isovelocity surface area flow convergence method used in estimating regurgitant valve flow rates. Recent advances in three-dimensional color Doppler flow imaging have created renewed interest in this method. Experimentation was based on the use of depth-averaged finite element models of the left heart. The heart models studied varied from "synthetic" representations to a model of a left heart traced from an actual echocardiographic image of a patient with a prolapsed mitral valve. The isovelocity surface area flow convergence method overestimated regurgitant flow rates throughout the Nyquist limits considered with a critical Nyquist limit in which this overestimation is minimized. The angle dependence of Doppler color flow imaging partially corrects for this overestimation. The isovelocity surface area flow convergence method is a viable alternative to methods currently in use. Through numerical experimentation, we have begun to shed light on the inaccuracies inherent in this flow convergence method.
通过数值实验,我们研究了用于估计瓣膜反流流速的等速表面积血流会聚法。三维彩色多普勒血流成像的最新进展重新引发了人们对该方法的兴趣。实验基于左心深度平均有限元模型。所研究的心脏模型从“合成”模型到从二尖瓣脱垂患者的实际超声心动图图像描绘的左心模型各不相同。在考虑的整个奈奎斯特极限范围内,等速表面积血流会聚法高估了反流流速,存在一个使这种高估最小化的临界奈奎斯特极限。多普勒彩色血流成像的角度依赖性部分校正了这种高估。等速表面积血流会聚法是当前所用方法的一种可行替代方法。通过数值实验,我们已开始揭示这种血流会聚法固有的不准确性。