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儿童患者颅脊柱野的计算机断层扫描模拟:提高治疗准确性和患者舒适度。

Computed tomographic simulation of craniospinal fields in pediatric patients: improved treatment accuracy and patient comfort.

作者信息

Mah K, Danjoux C E, Manship S, Makhani N, Cardoso M, Sixel K E

机构信息

Department of Medical Physics, Toronto-Sunnybrook Regional Cancer Center, and the University of Toronto, Ontario, Canada.

出版信息

Int J Radiat Oncol Biol Phys. 1998 Jul 15;41(5):997-1003. doi: 10.1016/s0360-3016(98)00108-4.

Abstract

PURPOSE

To reduce the time required for planning and simulating craniospinal fields through the use of a computed tomography (CT) simulator and virtual simulation, and to improve the accuracy of field and shielding placement.

METHODS AND MATERIALS

A CT simulation planning technique was developed. Localization of critical anatomic features such as the eyes, cribriform plate region, and caudal extent of the thecal sac are enhanced by this technique. Over a 2-month period, nine consecutive pediatric patients were simulated and planned for craniospinal irradiation. Four patients underwent both conventional simulation and CT simulation. Five were planned using CT simulation only. The accuracy of CT simulation was assessed by comparing digitally reconstructed radiographs (DRRs) to portal films for all patients and to conventional simulation films as well in the first four patients.

RESULTS

Time spent by patients in the CT simulation suite was 20 min on average and 40 min maximally for those who were noncompliant. Image acquisition time was <10 min in all cases. In the absence of the patient, virtual simulation of all fields took 20 min. The DRRs were in agreement with portal and/or simulation films to within 5 mm in five of the eight cases. Discrepancies of > or =5 mm in the positioning of the inferior border of the cranial fields in the first three patients were due to a systematic error in CT scan acquisition and marker contouring which was corrected by modifying the technique after the fourth patient. In one patient, the facial shield had to be moved 0.75 cm inferiorly owing to an error in shield construction.

CONCLUSIONS

Our analysis showed that CT simulation of craniospinal fields was accurate. It resulted in a significant reduction in the time the patient must be immobilized during the planning process. This technique can improve accuracy in field placement and shielding by using three-dimensional CT-aided localization of critical and target structures. Overall, it has improved staff efficiency and resource utilization.

摘要

目的

通过使用计算机断层扫描(CT)模拟器和虚拟模拟,减少规划和模拟颅脊髓野所需的时间,并提高野和屏蔽放置的准确性。

方法和材料

开发了一种CT模拟规划技术。该技术可增强对关键解剖特征(如眼睛、筛板区域和硬膜囊尾端范围)的定位。在2个月的时间里,对9例连续的儿科患者进行了颅脊髓照射的模拟和规划。4例患者同时接受了传统模拟和CT模拟。5例仅使用CT模拟进行规划。通过将数字重建射线照片(DRR)与所有患者的射野片进行比较,并与前4例患者的传统模拟片进行比较,评估CT模拟的准确性。

结果

患者在CT模拟室的平均停留时间为20分钟,不配合的患者最长为40分钟。所有病例的图像采集时间均<10分钟。在没有患者的情况下,所有野的虚拟模拟需要20分钟。8例中的5例,DRR与射野和/或模拟片的一致性在5毫米以内。前三例患者颅野下缘定位的差异≥5毫米是由于CT扫描采集和标记轮廓的系统误差,在第四例患者后通过修改技术进行了校正。在1例患者中,由于屏蔽构建错误,面部屏蔽不得不向下移动0.75厘米。

结论

我们的分析表明,颅脊髓野的CT模拟是准确的。它显著减少了患者在规划过程中必须固定的时间。该技术可通过使用关键和靶结构的三维CT辅助定位来提高野放置和屏蔽的准确性。总体而言,它提高了工作人员的效率和资源利用率。

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