Abe K, Ohishi Y, Onodera S, Kiyota H, Asano K
Department of Urology, Tokyo Jikei University School of Medicine.
Hinyokika Kiyo. 1998 Jun;44(6):415-7.
A 72-year-old man with the chief complaint of macrohematuria was referred to our hospital in February 1996. On transrectal examination, the prostate was stony hard without nodules. Cystoscopic findings and biopsies did not confirm a transitional cell carcinoma or carcinoma in situ in the bladder. However transurethral and transrectal biopsy specimens of prostate showed transitional cell carcinoma invading the prostate stroma. Pelvic CT scan revealed a lymph node metastasis in the left iliac artery region. Under the diagnosis of primary transitional cell carcinoma of the prostate, radical cystoprostatectomy and lymph node dissection were performed after two courses of neoadjuvant systemic chemotherapy. Pathologically no viable transitional cell carcinoma could be found in any of the specimens. Thus neo-adjuvant systemic chemotherapy was very effective in this case.
一名以肉眼血尿为主诉的72岁男性于1996年2月转诊至我院。经直肠检查发现，前列腺质地坚硬如石，无结节。膀胱镜检查结果及活检未证实膀胱存在移行细胞癌或原位癌。然而，前列腺的经尿道和经直肠活检标本显示移行细胞癌侵犯前列腺基质。盆腔CT扫描显示左髂动脉区域有淋巴结转移。在诊断为原发性前列腺移行细胞癌后，经过两个疗程的新辅助全身化疗后，进行了根治性膀胱前列腺切除术及淋巴结清扫术。病理检查在任何标本中均未发现存活的移行细胞癌。因此，新辅助全身化疗在该病例中非常有效。
