Gorskova E N, Tarasova L N, Teplova S N, Sevost'ianov E N, Alekhina T V
Vestn Oftalmol. 1998 May-Jun;114(3):26-8.
Local immunity was studied in 81 patients (146 eyes) aged 11-49 with keratoconus at different stages of the disease running different course. The concentrations of IgG, IgM, secretory IgA, lysozyme, immune complexes, C3 component of the complement, transferrin, and alpha 1-antitrypsin are increased in tears of patients with keratoconus, reflecting the activation of local immunity in this condition.
对81例年龄在11至49岁、处于圆锥角膜不同病程阶段的患者(146只眼)的局部免疫情况进行了研究。圆锥角膜患者泪液中IgG、IgM、分泌型IgA、溶菌酶、免疫复合物、补体C3成分、转铁蛋白和α1-抗胰蛋白酶的浓度升高,这反映了该疾病状态下局部免疫的激活。