Glogau R G
Department of Dermatology, University of California, San Francisco, USA.
Dermatol Surg. 1998 Aug;24(8):817-9. doi: 10.1111/j.1524-4725.1998.tb04257.x.
Axillary hyperhidrosis causes considerable emotional stress and is associated with extraordinary costs and limitations in clothing. Existing topical and surgical therapies are either ineffective or associated with unacceptable morbidity and sequelae. Botulinum A neurotoxin (Botox) has been shown to decrease sweating in normal skin and in palmar hyperhidrosis.
The current study was undertaken to demonstrate the utility of using Botox in the treatment of axillary hyperhidrosis.
Twelve patient with axillary hyperhidrosis underwent intradermal injection with 50 units of Botox in the axillary skin bilaterally.
All patients enjoyed relatively complete anhidrosis of the axillary skin in periods ranging from 4 to 7 months. Repeat injections produced similar results.
Botulinum A neurotoxin (Botox) is an elegant and simple treatment for axillary hyperhidrosis.
腋窝多汗症会导致相当大的情绪压力,并且与高昂的费用以及着装限制有关。现有的局部和手术治疗方法要么无效,要么伴有不可接受的发病率和后遗症。A型肉毒杆菌神经毒素(保妥适)已被证明可减少正常皮肤和手掌多汗症的出汗。
进行本研究以证明使用保妥适治疗腋窝多汗症的效用。
12例腋窝多汗症患者双侧腋窝皮肤进行皮内注射50单位保妥适。
所有患者在4至7个月期间腋窝皮肤相对完全无汗。重复注射产生类似结果。
A型肉毒杆菌神经毒素(保妥适)是一种治疗腋窝多汗症的简便有效方法。